Once Overlooked, Now Made Visible: ATL Proteins and DNA Repair
08-Sep-2009
Angew. Chem. Int. Ed., 2009, 48, 7293-7295 published on 08.09.2009
Angew. Chem. Int. Ed.
Damage report: Alkyltransferase-like proteins (ATLs) flip DNA lesions out of the DNA duplex but have no catalytic function. They act as recognition proteins that mark DNA lesions and allow repair (see picture; NER=nucleotide excision repair).