Flavin Induced DNA Photooxidation and Charge Movement Probed by Ultrafast Transient Absorption Spectroscopy

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Quantum yields of up to 14 % for the formation of a long-lived, charge-separated state can be achieved in flavin-capped DNA hairpins. The excited flavin state is quenched by electron-transfer processes from adjacent DNA bases. The introduction of multiple (dG:dC) base pairs leads to efficient hole trapping that competes with the charge recombination through dA-hopping processes.

TU München