Imidazolidinone-Derived Enamines: Nucleophiles with Low Reactivity
01-Aug-2012
Angew.Chem.Int.Ed., 2012, 51, 5739-5742 published on 25.04.2012
Angew.Chem.Int.Ed.
Angew.Chem.Int.Ed.
Extraordinarily weak nucleophiles: Enamines derived from imidazolidinones are 103–105 times less reactive than those derived from the Hayashi–Jørgensen catalyst. This finding explains the lower activity of MacMillan catalysts for enamine-activated reactions.
