Nucleophilicities and Lewis Basicities of Isothiourea Derivatives

J. Org. Chem., 2011, 76, 5104-5112 published on 13.05.2011
J. Org. Chem.

Rate and equilibrium constants for the reactions of a series of isothioureas with benzhydrylium ions have been measured photometrically. The data were employed to determine the nucleophilicities and nucleofugalities of isothioureas and compare them with those of other organocatalysts.

TU München