Photocontrolled chignolin-derived β-hairpin peptidomimetics
Chem. Commun., 2015, 51, 4001-4004 published on 19.01.2015
The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.